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The field of liver tumors in children, and in particular hepatoblastoma in infants and young children, has seen tremendous therapeutic advances over recent years. This has been achieved through a much better understanding of the biology of disease, improved diagnostic procedures, refined methods of pretreatment tumor staging, the implementation of highly efficient chemotherapy and surgery, detailed monitoring of toxicity, and careful follow-up strategies. International controlled trials have played a key role in these advances, and many leading figures in the trials are among the editors and authors of this book. Their principal goal in Hepatic Tumors in Children is to provide the reader with a complete update on this complex and rapidly evolving field. All aspects of an impressive success story are covered, disclosing how the outcome of a previously devastating disease has been so dramatically improved. This book will prove essential reading for all who are involved in the care of children with liver tumors.

Liver -- Cancer -- Treatment. --- Liver metastasis -- Treatment. --- Liver Neoplasms -- Therapy. --- Age Groups --- Digestive System Neoplasms --- Liver Diseases --- Neoplasms by Site --- Digestive System Diseases --- Persons --- Diseases --- Named Groups --- Neoplasms --- Liver Neoplasms --- Child --- Medicine --- Health & Biological Sciences --- Oncology --- Liver --- Tumors in children. --- Tumors --- Treatment. --- Pediatric oncology --- Medicine. --- Oncology. --- Pediatrics. --- Medicine & Public Health. --- Children --- Abdomen --- Biliary tract --- Oncology  . --- Paediatrics --- Pediatric medicine --- Health and hygiene

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Worldwide, there are an estimated 232, 000 new cases of pancreatic cancer annually. In the United States, it is the fourth leading cause of cancer death, and approximately 30,000 people die of pancreatic cancer each year. The disease is difficult to diagnose in its early stages, and most patients have incurable disease by the time they present with symptoms. The overall 5-year survival rate for this disease is less than 5%. In organizing this handbook, Dr. Neoptolemos and his co-editors will produce a distinguished Major Reference Work devoted to pancreatic cancer. This handbook will have widespread appeal among clinicians, pathologists and basic scientists who are now struggling to understand this complex and rapidly expanding field. Because of the recent and vast growth in both the clinical and scientific research being done in pancreatic cancer (there is currently an unprecedented investment by academia and industry in this field), each researcher’s knowledge of other specialty areas outside his or her own is now often quite limited. The aim of this book is to place these the tangible advances—those that are indispensable to all working on pancreatic cancer—readily at hand. The book will focus on advances that will not become dated, and the editors will choose authors who are the very best in each area.

Endocrine Gland Neoplasms --- Digestive System Neoplasms --- Pancreatic Diseases --- Neoplasms by Site --- Digestive System Diseases --- Endocrine System Diseases --- Pancreatic Neoplasms --- Diseases --- Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Pancreas --- Cancer --- Research. --- Diseases. --- Medicine. --- Cancer research. --- Endocrinology. --- Oncology. --- Biomedicine. --- Cancer Research. --- Oncology  . --- Internal medicine --- Hormones --- Tumors --- Endocrinology . --- Cancer research

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Carcinoma, Hepatocellular --- Hepacivirus --- Hepatitis B virus --- Hepatitis Delta Virus --- RNA Viruses --- Orthohepadnavirus --- Liver Neoplasms --- Flaviviridae --- Defective Viruses --- Hepatitis Viruses --- Adenocarcinoma --- Hepadnaviridae --- Digestive System Neoplasms --- Liver Diseases --- Vertebrates --- Carcinoma --- Viruses --- DNA Viruses --- Digestive System Diseases --- Neoplasms, Glandular and Epithelial --- Neoplasms by Site --- Diseases --- Neoplasms by Histologic Type --- Neoplasms --- virology.

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This book provides the reader with a multidisciplinary approach that is state of the art and reflects input from the European Neuroendocrine Tumor Society and the North American Neuroendocrine Tumor Society. In particular, the text focuses on the pathophysiology of neuroendocrine tumors and includes a comprehensive review of the most recent developments in understanding the complex hormone and receptor signaling that is important for the future development of potent pharmacological treatments. The volume reviews the pathological grading and staging systems providing useful clinical information for the treating clinician as well as a useful reference for pathologists. The clinical management of neuroendocrine tumors is reviewed enabling the treating physician to understand the diagnostic approaches to differentiating the various types of neuroendocrine tumors. In addition, the treatments are reviewed in great detail and include novel radiological, surgical, and chemotherapeutic approaches. The reader will utilize this book as both a comprehensive and quick reference guide through the use of diagnostic and treatment algorithms. Written by international experts in their particular field of study, Management of Pancreatic Neuroendocrine Tumors will be of great value to medical oncologists, endocrinologists, gastroenterologists, pathologists, surgeons, and diagnostic and interventional radiologists.

Medicine & Public Health. --- Gastroenterology. --- Endocrinology. --- Oncology. --- Diagnostic Radiology. --- Medicine. --- Radiology, Medical. --- Médecine --- Endocrinologie --- Gastroentérologie --- Cancérologie --- Neuroendocrine tumors --- Digestive System Neoplasms --- Neuroectodermal Tumors --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neoplasms, Germ Cell and Embryonal --- Neoplasms by Site --- Neoplasms by Histologic Type --- Neoplasms --- Diseases --- Pancreatic Neoplasms --- Neuroendocrine Tumors --- Diagnosis --- Medicine --- Health & Biological Sciences --- Gastroenterology --- Chemotherapy. --- Radiology. --- Tumors --- Oncology  . --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Internal medicine --- Digestive organs --- Hormones --- Gastroenterology . --- Endocrinology . --- Radiological physics --- Physics --- Radiation

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This fifth volume of the series, Methods of Cancer Diagnosis, Therapy, and Prognosis, discusses in detail the diagnosis, treatment, and prognosis of Liver Cancer. Both standard and emerging therapies for this cancer, written by expert oncologists/pathologists in this field, are included. This fully illustrated volume: Is divided into 7 sections: Applications of Imaging, Resectable Liver Cancer, Unresectable Liver Cancer, Hepatocellular Cancer, Liver Colorectal Metastasis, Biliary Cancer, and Splenic Cancer. Discusses imaging modalities for diagnosis, treatment assessment, and prognosis. Includes descriptions of radial magnetic resonance imaging, helical computed tomography, magnetic resonance imaging, FDG-PET, contrast-enhanced sonography, multidetector-row computed tomography, and single photon emission computed tomography. Presents imaging methods for localized fibrous tumors of the liver, abdominal neoplasms, cholangiocarcinoma, gall bladder carcinoma, hepatic cellular carcinoma, extrahepatic disease, intrahepatic disease, focal liver lesions, biliary cystic tumors, extra hepatic bile duct carcinoma, and splenic metastases. Highlights methods for treatment of hepatocellular carcinoma (HCC) with thalidomide and transarterial treatment of hepatic malignancies. Discusses postoperative interferon alpha treatment of patients with HCC. Details the methods of immunohistochemistry, tissue microarray, and proteomic analysis for diagnosis and prognosis. The technological advances presented in this volume are expected to expedite new discoveries and their translation to clinical practice. The field of oncology will benefit the most from these advanced methods, as a combination of therapies and personalized medicine will improve early detection of liver cancer and other cancer types. Professor Hayat has summarized the problems associated with the complexities of research publications and has been successful in editing a must-read volume for oncologists, cancer researchers, medical teachers and students of cancer biology.

Liver -- Cancer. --- Liver Neoplasms -- diagnosis. --- Liver Neoplasms -- therapy. --- Liver Neoplasms --- Neoplasm Metastasis --- Digestive System Neoplasms --- Neoplastic Processes --- Liver Diseases --- Digestive System Diseases --- Pathologic Processes --- Neoplasms by Site --- Neoplasms --- Diseases --- Pathological Conditions, Signs and Symptoms --- Oncology --- Medicine --- Health & Biological Sciences --- Oncology. --- Cancer --- Nursing. --- Liver --- Diagnosis. --- Prognosis. --- Treatment. --- Clinical nursing --- Nurses and nursing --- Nursing process --- Medicine. --- Cancer research. --- Radiotherapy. --- Surgical oncology. --- Biomedicine. --- Cancer Research. --- Surgical Oncology. --- Care of the sick --- Tumors --- Abdomen --- Biliary tract